Ozempic in the US: 0.5 mg a week

$1,027.51 every 4 weeks

Per dose (one week)
$256.88
1,027.51 ÷ 4 = $256.88
Per year (52 weeks)
$13,357.63
1,027.51 × 13 = $13,357.63
First year
$13,357.63

Pen (4 weekly doses): $1,027.51. Price as of . Source: Novo Nordisk, NovoCare list price page.

The first year, following the label’s dose schedule

If the dose went up at the fastest pace the label allows (4 weeks on each step) to 0.5 mg and stayed there for the rest of the year, the first year would cost $13,357.63:

  • Weeks 1 to 52 (0.25 and 0.5 mg), 13 pens at $1,027.51: 13 × 1,027.51 = $13,357.63.

It matches a year at the maintenance dose because the starting doses cost the same.

Price as of . Source: Novo Nordisk, NovoCare list price page. If your doctor extends a step or adjusts the dose, the math changes. Your doctor decides the dose.

  • Prices change; check the current price of your presentation with your pharmacy or insurance plan.
  • List price per pen published by Novo Nordisk on its NovoCare site: the price set before discounts or rebates, which most insured people do not pay. Amounts in US dollars, before insurance.
  • In the US, Ozempic is approved for adults with type 2 diabetes. What you pay depends on your insurance plan and pharmacy, and with coverage it is usually far below list price. The manufacturer also sells directly to people paying without insurance at lower self-pay prices; they change often and some depend on conditions, so this calculator does not use them.

How it is calculated

Each price has a date and a source. For the United States we use the list prices the manufacturers publish; for Spain and Mexico, our drug database, which stores the price per pack, the date, and the source for each country and brand. These are the figures the calculator uses:

MedicationWhat price it isDate and sourcePresentations
Mounjaro in the USList price (wholesale acquisition cost) per fill of 4 pens published by Lilly, the price at which Lilly sells to wholesalers.Price as of ; source: Lilly pricing information page.There is a price for 6 of its 6 presentations.
Ozempic in the USList price per pen published by Novo Nordisk on its NovoCare site: the price set before discounts or rebates, which most insured people do not pay.Price as of ; source: Novo Nordisk, NovoCare list price page.There is a price for 4 of its 4 presentations.
Wegovy in the USList price per package of 4 single-dose pens published by Novo Nordisk on its NovoCare site, the same for every strength: the price set before discounts or rebates, which most insured people do not pay.Price as of ; source: Novo Nordisk, NovoCare list price page.There is a price for 6 of its 6 presentations.
Wegovy pill in the USList price per bottle of 30 tablets published by Novo Nordisk on its NovoCare site, the same for every strength: the price set before discounts or rebates, which most insured people do not pay.Price as of ; source: Novo Nordisk, NovoCare list price page.There is a price for 4 of its 4 presentations.
Zepbound in the USList price (wholesale acquisition cost) per fill published by Lilly, the price at which Lilly sells to wholesalers. Lilly gives a range, $499 to $1,086.37 per fill, without saying which presentation (pens or vials) costs what, so the calculator works with both ends.Price as of ; source: Lilly pricing information page.The source does not give a price for each strength.
Mounjaro in SpainRetail price collected by OCU, a Spanish consumers’ organization. Since it is not funded, Mounjaro is not in the Nomenclátor and there is no official published price.Price as of ; source: OCU, Spanish consumers’ organization.There is a price for 6 of its 6 presentations.
Ozempic in SpainRetail price (PVP) including VAT from the billing list (Nomenclátor) of Spain’s Ministry of Health.Price as of ; source: Nomenclátor, the billing list of Spain’s Ministry of Health.There is a price for 5 of its 5 presentations.
Rybelsus in SpainRetail price (PVP) including VAT from the billing list (Nomenclátor) of Spain’s Ministry of Health.Price as of ; source: Nomenclátor, the billing list of Spain’s Ministry of Health.There is a price for 3 of its 3 presentations.
Wegovy in SpainRetail price collected by OCU, a Spanish consumers’ organization. Since it is not funded, Wegovy is not in the Nomenclátor and there is no official published price.Price as of ; source: OCU, Spanish consumers’ organization.There is a price for 5 of its 5 presentations.
Mounjaro in MexicoReference price reported by the press; it changes with promotions, availability, and region. Neither the manufacturer nor PROFECO, Mexico’s consumer protection agency, publishes an official price.Price as of ; source: POSTA México (news site).The source does not give a price for each strength.
Ozempic in MexicoPrice on Novo Nordisk Mexico’s online store, before patient-program discounts. Pharmacies may charge a different price: in September 2026, three chains sold the 0.25/0.5 mg pen for less.Price as of ; source: Novo Nordisk Mexico online store.There is a price for 2 of its 2 presentations.
Rybelsus in MexicoPrice on Novo Nordisk Mexico’s online store, before patient-program discounts. Pharmacies set their own prices. Mexico sells the 3, 7 and 14 mg tablets.Price as of ; source: Novo Nordisk Mexico online store.There is a price for 4 of its 4 presentations.
Wegovy in MexicoPrice on Novo Nordisk Mexico’s online store, before patient-program discounts. Pharmacies may charge a different price.Price as of ; source: Novo Nordisk Mexico online store.There is a price for 5 of its 5 presentations.
  • US list price. It is the price the manufacturer sets before insurance, discounts, or rebates (Lilly calls it the wholesale acquisition cost). Most people with insurance pay much less, and what you pay depends on your plan. The manufacturers also sell directly to people paying without insurance at lower self-pay prices; they change often and some depend on conditions such as refill timing, so this calculator does not use them. Where the page gives no date, the date shown is the day we checked it.
  • Doses per pack. Weekly pens hold 4 doses; the US Ozempic pen is counted as 4 weekly doses (Novo Nordisk defines a month as one pen), and a US Wegovy package holds 4 single-dose pens. Spain’s 1 mg Ozempic pen with 8 doses is counted separately. A box of Rybelsus and a bottle of Wegovy pills hold 30 tablets, one a day.
  • Periods. A dose is one week (or one day, for tablets). Four weeks are 4 doses or 28 tablets. A year is 52 weeks: 13 packs of 4 doses or 364 tablets, not 12 months.
  • Yearly cost. Only calculated for maintenance doses. Starting and step-up doses in the label last a few weeks, so multiplying them by a year makes no sense.
  • First year. When there is a price for each strength, the calculator adds up the first year following the label’s dose schedule: each step lasts what the label says, or the minimum of 4 weeks when the label says “at least 4 weeks”, and the rest of the year stays at the chosen dose. It is the fastest possible case; in practice, the doctor may extend a step. US list prices are the same for every strength of a brand, so the first year costs the same as a year at maintenance. It is not calculated for Zepbound in the US or for Mounjaro in Mexico, where the sources do not say which strengths each price covers, nor for Ozempic in Mexico, where the 0.25 mg starting dose has no pen of its own: it comes out of the 0.25/0.5 mg pen.
  • Rounding. Dollars and euros are rounded to the cent and pesos to the whole peso, once, at the end of each calculation. Where the source gives a range (Zepbound in the US, Mounjaro in Mexico), the calculation is done with each end.
  • Spain’s SNS prescription. With a funded prescription you do not pay the retail price but a copay that depends on income and personal situation. The calculator does not turn it into a figure; the rules are in the Ozempic price in Spain guide (in Spanish).
  • What it does not include. Doctor visits, lab tests, or needles when they are not in the box. Nor promotions, savings cards, or discounts, which are not the usual price.
  • No currency conversion. Each country’s figures stay in its own currency, because exchange rates change daily and prices are set separately in each market.

Prices change; check the current price of your presentation with your pharmacy or insurance plan.

Further reading

Sources

Sources for the prices, cited without links like every medicine price on this site, and for the dose schedules, with the access date.

  1. Novo Nordisk (NovoCare).Ozempic (semaglutide) injection 0.5 mg, 1 mg, 2 mg: list price and insurance coverage explained. Used for: Ozempic in the US, price as of September 23, 2026.accessed .
  2. Novo Nordisk (NovoCare).Wegovy (semaglutide): cost, coverage and savings resources ("Understanding list price"). Used for: Wegovy in the US, price as of September 23, 2026; Wegovy pill in the US, price as of September 23, 2026.accessed .
  3. Eli Lilly and Company.Mounjaro cost information: with or without insurance (list price, WAC from AnalySource accessed on January 1, 2026). Used for: Mounjaro in the US, price as of January 1, 2026.accessed .
  4. Eli Lilly and Company.Zepbound cost information: with or without insurance (list price, WAC from AnalySource accessed on January 1, 2026). Used for: Zepbound in the US, price as of January 1, 2026.accessed .
  5. Organización de Consumidores y Usuarios.Inyecciones para adelgazar: precios y financiación (1 de marzo de 2026) (in Spanish). Used for: Wegovy in Spain, price as of March 1, 2026; Mounjaro in Spain, price as of March 1, 2026.accessed .
  6. Ministerio de Sanidad.Nomenclátor de facturación de septiembre de 2026: búsqueda de Ozempic (PVP con IVA por código nacional) (in Spanish). Used for: Ozempic in Spain, price as of October 5, 2026.accessed .
  7. Ministerio de Sanidad.Nomenclátor de facturación de septiembre de 2026: búsqueda de Rybelsus (PVP con IVA por código nacional) (in Spanish). Used for: Rybelsus in Spain, price as of September 23, 2026.accessed .
  8. Novo Nordisk México.Tienda en línea de Novo Nordisk México: precio de Ozempic, Wegovy y Rybelsus por presentación (consultada el 5 de octubre de 2026; página de venta, citada sin enlace) (in Spanish). Used for: Ozempic in Mexico, price as of October 5, 2026; Wegovy in Mexico, price as of October 5, 2026; Rybelsus in Mexico, price as of October 5, 2026.accessed .
  9. POSTA México.¿Cuánto cuesta la tirzepatida en México? (19 de febrero de 2026) (in Spanish). Used for: Mounjaro in Mexico, price as of February 19, 2026.accessed .
  10. European Medicines Agency.Ozempic: EPAR product information (SmPC), last updated 25/08/2026. Dose schedule.accessed .
  11. European Medicines Agency.Wegovy: EPAR product information (SmPC), last updated 21/09/2026. Dose schedule.accessed .
  12. National Library of Medicine (DailyMed).Wegovy injection and tablets, prescribing information (DailyMed), revised 6/2026. Dose schedule.accessed .
  13. European Medicines Agency.Mounjaro: EPAR product information (SmPC), last updated 21/09/2026. Dose schedule.accessed .
  14. European Medicines Agency.Rybelsus: EPAR product information (SmPC), last updated 22/04/2026. Dose schedule.accessed .